Evolve BioSystems



“After speaking with TrueCommerce B2BGateway it was clear that they would be the right fit from a solution standpoint.  Their setup costs and transactional fees were also very affordable.” 

Jason Marrone | Evolve BioSystems  


Evolve BioSystems


Davis, CA 95618


Science / Medicine



Research shows that the newborn gut microbiome — the trillions of bacteria that live within the intestinal tract of newborns — plays a critical role in proper immune and metabolic development as well as meeting the newborn’s nutritional needs.

Disruption of the newborn gut microbiome can cause both acute and chronic health consequences. Based on novel discoveries of the unique partnership between human milk and B. infantis, Evolve has pioneered a microbiome-based approach to solving newborn gut dysbiosis.


Previously, Evolve BioSystems was reliant on Shopify’s API connection to fulfill orders.  With more business lining up, they wanted an EDI solution to streamline efficiency, with the ability to integrate with their 3PL.  Evolve does not have an ERP solution, which is not standard when trying to implement EDI into a business. TrueCommerce B2BGateway needed to accommodate the differences between Evolve’s multiple Sales channels and route the information flowing in directly to their 3PL for fulfillment.

Evolve BioSystems requires a cold shipped product, so fulfillment can become complex.  Evolve ships live organisms with ice packs to hospitals across the country.  Because of the nature of this product, they need to ship Monday-Wednesday for two day shipments, Thursday shipments go overnight, and they will occasionally ship Friday for a Saturday delivery depending on cutoff times.  These deadlines are strict.

Any orders that are placed on Friday afternoon, all the way through Monday morning, would be shipped out that Monday afternoon.  Due to the complexity of this schedule, their fulfillment solution needs to distinguish the transits times as well as the cutoff times and ship accordingly.  Sometimes due to inclement weather scenarios such as a really hot day, they need to upgrade the shipping to overnight even if the order was placed for two day shipping.  The consumer actually never chooses a one or two day shipping method, however they are choosing the date for which they want the product delivered.  On top of these complexities, when an order is placed outside of their Shopify store or if they place a manual order, they can not utilize their 3PL’s algorithm because it can only tie into Shopify. The order only comes in as the title of the shipping method, for example, ‘Expedited’.


TrueCommerce B2BGateway has created cross reference tables for Evolve that can translate “expedited” to the appropriate shipping method and shipping code.

Essentially, TrueCommerce B2BGateway’s solution translates these “non-Shopify” orders and sends them to their 3PL with the appropriate shipping code, calculating which day of the week the order should be shipped and which day it should arrive.

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About TrueCommerce B2BGateway

TrueCommerce B2BGateway provides fully managed Electronic Data Interchange (EDI) & API Connectivity Solutions for Shopify users. TrueCommerce B2BGateway’s cloud-based solutions allow Shopify users to communicate seamlessly with their customers and 3PL’s. Our fully managed solutions for Shopify are 100% built and maintained by TrueCommerce B2BGateway developers which gives us the ability to offer a customized solution that fits your business model. EDI eliminates data re-entry, drastically reduces errors, cuts down on labor requirements and speeds up the ‘order to payment’ cash cycle. TrueCommerce B2BGateway meets all trading partner requirements and regulations and we support all global standards and communication methods.

In addition to our global headquarters in Rhode Island, TrueCommerce B2BGateway has offices in Ireland, Australia and the UK that enable us to offer unparalleled support across all time zones.

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